منابع مشابه
RNA Relics and Origin of Life
A number of small RNA sequences, located in different non-coding sequences and highly preserved across the tree of life, have been suggested to be molecular fossils, of ancient (and possibly primordial) origin. On the other hand, recent years have revealed the existence of ubiquitous roles for small RNA sequences in modern organisms, in functions ranging from cell regulation to antiviral activi...
متن کاملRNA Second Messengers and Riboswitches: Relics from the RNA World?
C ompelling evidence supports the hypothesis that modern cells descended from organisms whose components were made entirely of RNA. Scientists who helped formulate this “RNA World” hypothesis for the evolution of life have identified many characteristics of modern cells that strongly suggest RNA once ruled the planet. For example, the existence of selfcleaving and self-splicing ribozymes that c...
متن کاملOrigin of Life and RNA; Achievements and Disillusions
In the best articles, generally those dealing with basic Chromosome Puffs research, the combination of depth and accessibility is impressive. One on Hox genes introduces the notion of The Science Times Book of Genetics a conserved body plan among species, illustrating the Edited by Nicholas Wade point with the fauna of Star Trek, and continues with New York: The Lyons Press (1999). 256 pp. an e...
متن کاملRNA Catalysis, Thermodynamics and the Origin of Life
The RNA World Hypothesis posits that the first self-replicating molecules were RNAs. RNA self-replicases are, in general, assumed to have employed nucleotide 5'-polyphosphates (or their analogues) as substrates for RNA polymerization. The mechanism by which these substrates might be synthesized with sufficient abundance to supply a growing and evolving population of RNAs is problematic for evol...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2009
ISSN: 1422-0067
DOI: 10.3390/ijms10083420